A set of four different, problem-based or resource-based, bioinformatics workshops. Class will consist of a lecture and hands-on time. Each course will accommodate only 20 people so register early. Courses are: Bioinformatics Quick Start: The course provides an introduction to aspects of bioinformatics such as accessing, analyzing, and interpreting biological data using NCBI databases and tools. Making Sense of DNA and Protein Sequences: in this mini-course, we will find a gene within a eukaryotic DNA sequence. We will then predict the function of the implied protein product by seeking sequence similarities to proteins of documented function using BLAST and other tools. Finally, we will find a 3D modeling template for this protein sequence using a Conserved Domain Database Search. Correlating Disease Genes and Phenotypes: We will learn to determine what is known about a disease and the gene associated with it. We will then elucidate the biochemical and structural basis for the phenotype caused by the mutant protein. Microbial Genome Quick Start: in this mini-course, you will learn how to access the microbial genome sequences and annotations, how to navigate through and download the gene and protein datasets, and will be introduced to the available genomic and comparative genomic analysis tools.

Intended Audience: faculty, graduate students, researchers, staff

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