- African American Literature (General Collections)
- Africana studies and African American studies special collections
- Afrofuturism
- American Poetry Review Records
- American studies, history, and literature: Modern period
- American studies, history, and literature: North America, colonial era to ca. 1800
- Banned Books Collection
- Caroline F. Schimmel Fiction Collection of Women in the American Wilderness
- Collection of British and American Fiction, 1660-1830
- Comics and Graphic Novels Collection
- Edwin Forrest Library and collection
- Francis Hopkinson collections
- Gotham Book Mart Collection
- Horace Howard Furness Memorial Library (Furness Shakespeare Library)
- Immigrant and Refugee Experiences in Children’s and Young Adult Literature
- Immigrant Literature
- James T. Farrell collection
- Jean-François Vilain and Roger S. Wieck Collection of Private Presses, Ephemera, & Related References
- Joanna Banks Collection of African American Books
- Mark B. Adams Science Fiction Collection
- Printing and publishing history
- Ross Bible Collection
- Short Title Catalogue (STC) Collection of early English printed books to 1640
- Theodore Dreiser Collection
- Waldo Frank papers
- Walt Whitman Collections
